Common use

Donamem is used to manage Alzheimer's disease by improving brain function and helping with memory loss. It contains two active ingredients: Donepezil and Memantine. Donepezil increases levels of the chemical acetylcholine, while Memantine regulates the activity of glutamate. These components work together to balance chemicals in the brain and support nerve signals. This medication helps slow down the progression of Alzheimer's symptoms and supports overall brain health.

Dosage and direction

Consult a healthcare professional for the appropriate dosage and treatment duration. Take the tablet as a whole with an adequate amount of water without breaking or crushing it. Avoid exceeding the prescribed dose and adhere to the recommended schedule.

Precautions

Special caution should be taken when administering Donamem to patients with a history of ulcer disease or asthma. It requires careful management under medical supervision. Patients with a history of cardiac conditions should also use this medication cautiously due to potential heart rate changes.
Donamem may require dose adjustments in individuals with liver disease to avoid potential side effects. Individuals with kidney disease should be closely monitored while taking Donamem, as it may affect kidney function.

Contraindications

Donamem is contraindicated in individuals with a known hypersensitivity to either donepezil or memantine. It should not be used by patients with severe renal impairment or those who have experienced seizures.

Possible side effect

Donamem common side effects include headache, frequent diarrhea, dizziness (feeling lightheaded or unsteady), tiredness (excessive fatigue), and sudden, painful muscle cramps.

Drug interaction

Donamem may interact with anticholinergics (e.g., atropine and scopolamine), cholinomimetics (e.g., bethanechol and carbachol), and NMDA antagonists (e.g., amantadine and ketamine).

Missed dose

If you forget to take a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue your regular dosing schedule.

Overdose

An overdose of Donamem may result in severe nausea, vomiting, muscle weakness, and slow heart rate. Immediate medical attention is required in such scenarios.

Storage

Store the tablets in a cool and dry place, away from direct sunlight, keeping them out of reach of children and pets.